Methanolic Extract of Ripen Musa sapientum Lowers Fasting Blood Glucose of Non Diabetic Swiss Albino Mice

Authors

  • Mohammad Asaduzzaman Department of Biochemistry and Molecular Biology, Noakhali Science and Technology University, Noakhali, Bangladesh
  • Md. Ala Uddin Square Hospital, Dhaka, Bangladesh
  • Tasnuva Ferdous Department of Biochemistry and Molecular Biology, Primeasia University, Dhaka, Bangladesh
  • Abdus Salam Mondol Department of Public Health Nutrition, Primeasia University, Dhaka, Bangladesh
  • Md. Ruhul Amin Biotechnology and Genetic Engineering, University of Development Alternative, Dhaka, Bangladesh
  • Rasel Ahmed Department of Biochemistry and Molecular Biology, Primeasia University, Dhaka, Bangladesh
  • Md. Saad Ibn Hossain Department of Biochemistry and Molecular Biology, Primeasia University, Dhaka, Bangladesh

Keywords:

Musa sapientum, Fasting Blood Glucose, folk medicine.

Abstract

Musa sapientum (M. sapientum) commonly known as ‘banana’ is widely used folk medicine for the treatment of various ailments including diarrhea, wounds, stomach ulcer, diabetes, heart burn, inflammation and others. The medicinal use of this study focuses on the potential of ripen whole banana fruits in lowering blood sugar. Banana fruits were dried and turned into powder form to administer to Albino rats. Thirty Swiss Albino rats served as experimental animals. They were randomly assigned in six groups. The first group (5 animals) served as controls were fasted and only fed a glucose solution of 4 g/kg. The second group served as the experimental animals where Glibenclamide (10mg/kg) solution with 4g/kg glucose solution was administered orally. Initial fasting blood sugar levels of both treatments showed significant glucose absorption. Fasting blood sugar for other treatment groups with 50, 100, 200 and 400mg/kg ripen Musa sapientum extract with 4g/kg glucose solution showed significant results. The result revealed that banana extract has the potential for lowering blood glucose in Swiss Albino Rats. This implies that banana fruit can be used as herbal medicine to lower blood glucose.

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Published

2022-09-13

How to Cite

Mohammad Asaduzzaman, Md. Ala Uddin, Tasnuva Ferdous, Abdus Salam Mondol, Md. Ruhul Amin, Rasel Ahmed, & Md. Saad Ibn Hossain. (2022). Methanolic Extract of Ripen Musa sapientum Lowers Fasting Blood Glucose of Non Diabetic Swiss Albino Mice. International Journal of Recent Innovations in Academic Research, 6(9), 18–22. Retrieved from https://ijriar.com/index.php/ijriar/article/view/458